Tissue expression
Cell line expression
Protein structure
MAP3K20
Mitogen-activated protein kinase kinase kinase 20MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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antibodies-online | ABIN393700 | 5 references | Monoclonal |
WB
EL
ICC
IHC |
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Proteintech Group | 14945-1-AP | 6 references | Polyclonal |
WB
EL
ICC
IHC |
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Novus Biologicals | NBP1-90367 | 1 references | Polyclonal |
WB
ICC
IHC
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LSBio | LS-C349093 | Polyclonal |
WB
ICC
IHC
|
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Abnova Corporation | H00051776-M03 | 2 references | Monoclonal |
ICC
IHC |
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Supportive data in Antibodypedia
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Recommended by provider