Tissue expression
Cell line expression
Protein structure
H1-2
H1.2 linker histone, cluster memberH1.2, H1c, H1F2, H1s-1, HIST1H1C
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
Top validated antibodies |
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Proteintech Group | 19649-1-AP | 18 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | PA5-112452 | Polyclonal |
WB
EL
ICC
IP
ChIP
OA |
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LSBio | LS-C676847 | Polyclonal |
WB
EL
ICC
IP |
||
GeneTex | GTX122561 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
NovoPro Bioscience Inc. | 111403 | Polyclonal |
WB
EL
ICC
IP
IHC
|
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