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Protein structure
STING1
Stimulator of interferon response cGAMP interactor 1ERIS, FLJ38577, MITA, MPYS, NET23, STING, TMEM173
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Top validated antibodies |
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| Proteintech Group |  19851-1-AP |
290 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Invitrogen Antibodies | PA5-23381 |
3 references | Polyclonal |
WB
EL
ICC
IHC
FC
OA
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| Novus Biologicals | NBP2-24683 |
15 references | Polyclonal |
WB
ICC
IHC
FC
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| R&D Systems | MAB7169 |
12 references | Monoclonal |
WB
ICC
FC
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| NovoPro Bioscience Inc. | 116105 |
Polyclonal |
WB
EL
ICC
IP
IHC
FC
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