H1-10

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]

Description

H1.10 linker histone

Tissue specificity

Tissue enriched (bone marrow)

Subcell location

Nucleoplasm, Nucleoli, Nucleoli rim

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

3 (129314771 - 129316286)

Ensembl ID

ENSG00000184897  (ver. 103.38)

Orthologs

Mouse H1f10: ENSMUSG00000044927

UniProt

Q92522

neXtProt

NX_Q92522

Human splice variants
Mouse splice variants

Protein structure