NB100-56542
antibody from Novus Biologicals
Targeting: IKBKG
FIP-3, FIP3, Fip3p, IKK-gamma, IP1, IP2, NEMO, ZC2HC9
Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- NB100-56542 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-56542, RRID:AB_838430
- Product name
- Mouse Monoclonal IKK gamma Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. A 48 kDa band is observed.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains.
Identification of new IκBα complexes by an iterative experimental and mathematical modeling approach.
Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway.
A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha.
The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL.
Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis.
Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke.
Ren T, Takahashi Y, Liu X, Loughran TP, Sun SC, Wang HG, Cheng H
Oncogene 2015 Jan 15;34(3):334-45
Oncogene 2015 Jan 15;34(3):334-45
Identification of new IκBα complexes by an iterative experimental and mathematical modeling approach.
Konrath F, Witt J, Sauter T, Kulms D
PLoS computational biology 2014 Mar;10(3):e1003528
PLoS computational biology 2014 Mar;10(3):e1003528
Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway.
Harikumar KB, Sung B, Pandey MK, Guha S, Krishnan S, Aggarwal BB
Molecular pharmacology 2010 May;77(5):818-27
Molecular pharmacology 2010 May;77(5):818-27
A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha.
Siggs OM, Berger M, Krebs P, Arnold CN, Eidenschenk C, Huber C, Pirie E, Smart NG, Khovananth K, Xia Y, McInerney G, Karlsson Hedestam GB, Nemazee D, Beutler B
Proceedings of the National Academy of Sciences of the United States of America 2010 Feb 16;107(7):3046-51
Proceedings of the National Academy of Sciences of the United States of America 2010 Feb 16;107(7):3046-51
The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL.
Lamothe B, Campos AD, Webster WK, Gopinathan A, Hur L, Darnay BG
The Journal of biological chemistry 2008 Sep 5;283(36):24871-80
The Journal of biological chemistry 2008 Sep 5;283(36):24871-80
Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis.
Wunderlich FT, Luedde T, Singer S, Schmidt-Supprian M, Baumgartl J, Schirmacher P, Pasparakis M, Brüning JC
Proceedings of the National Academy of Sciences of the United States of America 2008 Jan 29;105(4):1297-302
Proceedings of the National Academy of Sciences of the United States of America 2008 Jan 29;105(4):1297-302
Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke.
Han HS, Karabiyikoglu M, Kelly S, Sobel RA, Yenari MA
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003 May;23(5):589-98
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003 May;23(5):589-98
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Simple Western: IKK gamma Antibody (72C627) [NB100-56542] - Simple Western lane view shows a specific band for IKK gamma in 0.05 mg/ml of Jurkat lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: IKK gamma Antibody (72C627) [NB100-56542] - Analysis using IKK gamma (NEMO) antibody. Lysate from 1) human Jurkat and 2) mouse NIH 3T3 cells probed with IKK gamma antibody at 2 ug/ml.