ABIN954852

antibody from antibodies-online

Targeting: PPP4R3B FLFL2, FLJ31474, KIAA1387, PSY2, SMEK2

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN954852

Provider

antibodies-online

Product name

anti-SMEK Homolog 2, Suppressor of Mek1 (Dictyostelium) (SMEK2) (AA 719-748), (C-Term) antibody

Antibody type

Polyclonal

Description

Affinity chromatography on Protein A

Reactivity

Human

Host

Rabbit

Epitope

C-Term, AA 719-748

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication.

Chowdhury D, Xu X, Zhong X, Ahmed F, Zhong J, Liao J, Dykxhoorn DM, Weinstock DM, Pfeifer GP, Lieberman J
Molecular cell 2008 Jul 11;31(1):33-46

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Loss of SMEK, a novel, conserved protein, suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects.

Mendoza MC, Du F, Iranfar N, Tang N, Ma H, Loomis WF, Firtel RA
Molecular and cellular biology 2005 Sep;25(17):7839-53

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A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity.

Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, Sonenberg N, Hafen E, Raught B, Aebersold R
Molecular & cellular proteomics : MCP 2005 Nov;4(11):1725-40

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB