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PRKN
Parkin RBR E3 ubiquitin protein ligaseAR-JP, PARK2, parkin, PDJ
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-13399 |
2 references | Polyclonal |
WB
ICC
IHC
FC
OA
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| Novus Biologicals | NBP2-67017 |
2 references | Monoclonal |
WB
ICC
IP
IHC
FC
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| Proteintech Group | 14060-1-AP |
71 references | Polyclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN393540 |
5 references | Monoclonal |
WB
EL
ICC
IHC
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| Abgent | AP6402a |
Polyclonal |
WB
ICC
IHC
FC
|
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