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Cell line expression
Protein structure
DPM1
Dolichyl-phosphate mannosyltransferase subunit 1, catalyticCDGIE, MPDS
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Top validated antibodies |
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| Proteintech Group |  12403-2-AP |
2 references | Polyclonal |
WB
EL
IHC
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| Novus Biologicals | NBP1-05034 |
1 references | Polyclonal |
WB
EL
IHC
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| Cusabio Biotech Co., Ltd | CSB-PA007134LA01HU |
Polyclonal |
WB
EL
ICC
IHC
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| Biorbyt | orb1420068 |
Polyclonal |
WB
EL
ICC
IHC
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| LSBio | LS-C671573 |
Polyclonal |
WB
EL
ICC
IHC
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