DHX33

This gene encodes a member of the DEAD box protein family. The DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Description

DEAH-box helicase 33

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

17 (5440917 - 5468982)

Ensembl ID

ENSG00000005100  (ver. 103.38)

Orthologs

Mouse Dhx33: ENSMUSG00000040620

UniProt

Q9H6R0

neXtProt

NX_Q9H6R0

Human splice variants
Mouse splice variants

Protein structure