Tissue expression
Cell line expression
Protein structure
MSL3
MSL complex subunit 3MSL3L1
This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]
Top validated antibodies |
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Invitrogen Antibodies | PA5-28282 | Polyclonal |
WB
ICC
IP
OA |
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antibodies-online | ABIN2033977 | Polyclonal |
WB
ICC
IP
|
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GeneTex | GTX105652 | Polyclonal |
WB
ICC
IP
|
||
Abnova Corporation | H00010943-B01 | 1 references | Polyclonal |
WB
ICC |
|
Biorbyt | orb451017 | Polyclonal |
WB
EL
ICC
IHC |
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