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Protein structure
ABCB4
ATP binding cassette subfamily B member 4GBD1, MDR2, MDR3, PFIC-3, PGY3
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online |  ABIN2840588 |
2 references | Polyclonal |
WB
IHC
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| Boster Biological Technology | PB9275 |
Polyclonal |
WB
ICC
IHC
FC
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| OriGene | AP13075PU-N |
1 references | Polyclonal |
WB
IHC
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| Invitrogen Antibodies | PA5-78692 |
Polyclonal |
WB
IHC
FC
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| Abnova Corporation | PAB4698 |
1 references | Polyclonal |
WB
IHC
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