Tissue expression
Cell line expression
Protein structure
FBXL3
F-box and leucine rich repeat protein 3FBL3, FBL3A, FBXL3A
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online | 5 references | Monoclonal |
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| GeneTex | 2 references | Polyclonal |
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| LSBio | Monoclonal |
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| Novus Biologicals | 2 references | Polyclonal |
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| OriGene | Polyclonal |
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