Tissue expression
Cell line expression
Protein structure
MAP3K14
Mitogen-activated protein kinase kinase kinase 14FTDCR1B, HS, HSNIK, NIK
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Abnova Corporation | ![]() |
3 references | Polyclonal |
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Santa Cruz Biotechnology | ![]() |
2 references | Monoclonal |
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Biorbyt | ![]() |
Polyclonal |
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