Tissue expression
Cell line expression
Protein structure
CRY1
Cryptochrome circadian regulator 1PHLL1
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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Proteintech Group | 13474-1-AP | 9 references | Polyclonal |
WB
EL
ICC
IHC |
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Invitrogen Antibodies | PA5-13124 | 2 references | Polyclonal |
WB
IHC
OA
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OriGene | AM31168PU-N | Monoclonal |
WB
EL
ICC
IHC |
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Novus Biologicals | H00001407-M01 | Monoclonal |
WB
EL
ICC
IHC |
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antibodies-online | ABIN2840599 | 4 references | Polyclonal |
WB
IHC |
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Supportive data in Antibodypedia
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Recommended by provider