Tissue expression
Cell line expression
Protein structure
MASP2
Mannan binding lectin serine peptidase 2MASP1P1
This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Top validated antibodies |
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antibodies-online | ABIN676223 | Polyclonal |
WB
EL
ICC
IHC |
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Atlas Antibodies | HPA029313 | Polyclonal |
WB
ICC
IHC
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LSBio | LS-B14682 | Polyclonal |
WB
EL
IHC
|
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Invitrogen Antibodies | PA5-56111 | Polyclonal |
WB
ICC
IHC
|
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Novus Biologicals | NBP1-81259 | Polyclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider