Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
MBTPS2
Membrane bound transcription factor peptidase, site 2KFSD, S2P
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response. [provided by RefSeq, Aug 2009]
Top validated antibodies |
|||||
| antibodies-online |  ABIN953342 |
5 references | Polyclonal |
WB
IHC
|
|
| Novus Biologicals | H00051360-M01 |
Monoclonal |
WB
EL
ICC
|
||
| NovoPro Bioscience Inc. | 139085 |
Polyclonal |
WB
EL
IHC
|
||
| Biorbyt | orb1274959 |
Polyclonal |
WB
EL
IHC
|
||
| Acris Antibodies GmbH | AP52627PU-N |
Polyclonal |
WB
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider