EIPR1

This gene has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11. [provided by RefSeq, Dec 2008]

Description

EARP complex and GARP complex interacting protein 1

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Nucleoli, Intermediate filaments

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

2 (3188925 - 3377830)

Ensembl ID

ENSG00000032389  (ver. 103.38)

Orthologs

Mouse Eipr1: ENSMUSG00000036613

UniProt

Q53HC9

neXtProt

NX_Q53HC9

Human splice variants
Mouse splice variants

Protein structure