Tissue expression
Cell line expression
Protein structure
ZIC2
Zic family member 2HPE5
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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Invitrogen Antibodies | PA5-113616 | Polyclonal |
WB
IP
IHC
OA |
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NSJ Bioreagents | RQ6448 | Polyclonal |
WB
EL
ICC
FC |
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Boster Biological Technology | A03936-2 | Polyclonal |
WB
EL
ICC
FC |
||
GeneTex | GTX60258 | Polyclonal |
WB
EL
ICC
IHC |
||
LSBio | LS-C30460 | Polyclonal |
WB
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider