Tissue expression
Cell line expression
Protein structure
ATP6V1H
ATPase H+ transporting V1 subunit HCGI-11, SFD, SFDalpha, SFDbeta, VMA13
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Top validated antibodies |
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Atlas Antibodies | HPA023421 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
GeneTex | GTX110778 | 2 references | Polyclonal |
WB
ICC
IHC
|
|
Invitrogen Antibodies | PA5-22134 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Proteintech Group | 26683-1-AP | 5 references | Polyclonal |
WB
EL
IP
|
|
Novus Biologicals | NBP1-85668 | 1 references | Polyclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
Data presented on provider website
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Recommended by provider