Tissue expression
Cell line expression
Protein structure
TBXAS1
Thromboxane A synthase 1CYP5, CYP5A1, THAS, TS, TXAS, TXS
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Top validated antibodies |
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OriGene | TA501358 | 1 references | Monoclonal |
WB
ICC
IHC
FC |
|
Novus Biologicals | NBP2-02710 | 1 references | Monoclonal |
WB
ICC
IHC
FC |
|
Proteintech Group | 11321-1-AP | 3 references | Polyclonal |
WB
EL
IHC
|
|
Invitrogen Antibodies | CF501357 | Monoclonal |
WB
ICC
IHC
FC |
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GeneTex | GTX83521 | Monoclonal |
WB
ICC
IHC
FC |
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Enhanced validation
Supportive data in Antibodypedia
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Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider