Tissue expression
Cell line expression
Protein structure
MXD1
MAX dimerization protein 1bHLHc58, MAD, MAD1
This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Top validated antibodies |
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Proteintech Group | 19547-1-AP | 1 references | Polyclonal |
WB
EL
IP
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Invitrogen Antibodies | 19547-1-AP | Polyclonal |
WB
IP
OA
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NovoPro Bioscience Inc. | 112910 | Polyclonal |
WB
EL
IP
|
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Atlas Antibodies | HPA001599 | Polyclonal |
IHC
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Abnova Corporation | PAB28456 | Polyclonal |
ICC
IHC |
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider