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LearnTissue expression
Cell line expression
Protein structure
LZTS1
Leucine zipper tumor suppressor 1FEZ1
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq, Nov 2009]
Top validated antibodies |
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| Proteintech Group |  20878-1-AP |
1 references | Polyclonal |
WB
EL
ICC
IP
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| Invitrogen Antibodies | 20878-1-AP |
Polyclonal |
WB
ICC
IP
OA
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| NovoPro Bioscience Inc. | 112420 |
Polyclonal |
WB
EL
ICC
IP
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| Wuhan Fine Biotech Co., Ltd. | FNab04917 |
Polyclonal |
WB
EL
ICC
IP
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| GeneTex | GTX117376 |
1 references | Polyclonal |
WB
IHC
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