ARSF

This gene is a member of the sulfatase family, and more specifically, the arylsulfatase subfamily. Members of the subfamily share similarity in sequence and splice sites, and are clustered together on chromosome X, suggesting that they are derived from recent gene duplication events. Sulfatases are essential for the correct composition of bone and cartilage matrix. The activity of this protein, unlike that of arylsulfatase E, is not inhibited by warfarin. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]

Description

Arylsulfatase F

Tissue specificity

Tissue enhanced (brain, kidney, skin)

Subcell location

Cytosol

Predicted location

Membrane, Secreted in other tissues

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

X (3041471 - 3112727)

Ensembl ID

ENSG00000062096  (ver. 103.38)

Orthologs

-

UniProt

P54793

neXtProt

NX_P54793

Human splice variants

Protein structure