ADAM7

This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma. [provided by RefSeq, Oct 2011]

Description

ADAM metallopeptidase domain 7

Tissue specificity

Tissue enriched (epididymis)

Predicted location

Intracellular, Membrane

Protein family

Disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

8 (24440930 - 24526970)

Ensembl ID

ENSG00000069206  (ver. 103.38)

Orthologs

Mouse Adam7: ENSMUSG00000022056

UniProt

Q9H2U9

neXtProt

NX_Q9H2U9

Human splice variants
Mouse splice variants

Protein structure