Tissue expression
Cell line expression
Protein structure
TRPM5
Transient receptor potential cation channel subfamily M member 5LTRPC5, MTR1
This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele. [provided by RefSeq, Oct 2010]
Top validated antibodies |
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Proteintech Group | 18027-1-AP | 2 references | Polyclonal |
WB
EL
ICC
IP
IHC
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LSBio | LS-C432115 | Polyclonal |
WB
IHC |
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Invitrogen Antibodies | 18027-1-AP | Polyclonal |
WB
IP
IHC
OA |
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NovoPro Bioscience Inc. | 116411 | Polyclonal |
WB
EL
ICC
IP |
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GeneTex | GTX54864 | 1 references | Polyclonal |
WB
IHC |
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Supportive data in Antibodypedia
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