Tissue expression
Cell line expression
Protein structure
CHFR
Checkpoint with forkhead and ring finger domainsFLJ10796, RNF196
This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014]
Top validated antibodies |
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| Novus Biologicals | 11 references | Monoclonal |
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| Abnova Corporation | 7 references | Monoclonal |
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| Proteintech Group | 6 references | Polyclonal |
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| antibodies-online | 7 references | Monoclonal |
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| LSBio | Polyclonal |
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