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XRCC1
X-ray repair cross complementing 1RCC
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  MA1-12640 |
7 references | Monoclonal |
WB
ICC
IP
IHC
OA
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| Atlas Antibodies | HPA006717 |
Polyclonal |
WB
ICC
IHC
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| antibodies-online | ABIN2840381 |
2 references | Polyclonal |
WB
ICC
IHC
FC
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| GeneTex | GTX21838 |
2 references | Monoclonal |
WB
ICC
IP
IHC
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| Boster Biological Technology | A00571 |
Polyclonal |
WB
EL
ICC
IHC
FC
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