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PTGS2
Prostaglandin-endoperoxide synthase 2COX2
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-14568 |
61 references | Monoclonal |
WB
ICC
IHC
OA
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| Novus Biologicals | NB100-868 |
6 references | Polyclonal |
WB
EL
ICC
IHC
FC
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| Proteintech Group | 12375-1-AP |
190 references | Polyclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN257712 |
4 references | Polyclonal |
WB
EL
ICC
IHC
FC
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| R&D Systems | AF4198 |
2 references | Polyclonal |
WB
ICC
FC
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