Tissue expression
Cell line expression
Protein structure
EIF4G3
Eukaryotic translation initiation factor 4 gamma 3eIF4GII
The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. [provided by RefSeq, May 2016]
Top validated antibodies |
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Proteintech Group | 11281-1-AP | 1 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | PA5-31101 | 2 references | Polyclonal |
WB
ICC
IHC
OA |
|
GeneTex | GTX118109 | 1 references | Polyclonal |
WB
ICC
IP
IHC |
|
Novus Biologicals | NBP2-16309 | 1 references | Polyclonal |
WB
ICC
IP
IHC |
|
LSBio | LS-C133562 | Monoclonal |
WB
EL
IHC
|
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider