Tissue expression
Cell line expression
Protein structure
MOCOS
Molybdenum cofactor sulfuraseFLJ20733, HMCS, MOS
This gene encodes an enzyme that sulfurates the molybdenum cofactor which is required for activation of the xanthine dehydrogenase (XDH) and aldehyde oxidase (AO) enzymes. XDH catalyzes the conversion of hypoxanthine to uric acid via xanthine, as well as the conversion of allopurinol to oxypurinol, and pyrazinamide to 5-hydroxy pyrazinamide. Mutations in this gene cause the metabolic disorder classical xanthinuria type II which is characterized by the loss of XDH/XO and AO enzyme activity, decreased levels of uric acid in the urine, increased levels of xanthine and hypoxanthine in the serum and urine, formation of xanthine stones in the urinary tract, and myositis due to tissue deposition of xanthine. [provided by RefSeq, Apr 2017]
Top validated antibodies |
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Invitrogen Antibodies | 16395-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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Proteintech Group | 16395-1-AP | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
NovoPro Bioscience Inc. | 112724 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
Novus Biologicals | NBP2-14243 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Atlas Antibodies | HPA047958 | Polyclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider