NEBL

This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

Description

Nebulette

Tissue specificity

Tissue enriched (heart muscle)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

10 (20779973 - 21293011)

Ensembl ID

ENSG00000078114  (ver. 103.38)

Orthologs

Mouse Nebl: ENSMUSG00000053702

UniProt

O76041

neXtProt

NX_O76041

Human splice variants
Mouse splice variants

Protein structure