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DLD
Dihydrolipoamide dehydrogenaseDLDH, E3, GCSL, LAD, OGDC-E3
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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| Proteintech Group |  16431-1-AP |
4 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | 16431-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| OriGene | AP07395PU-N |
Polyclonal |
WB
EL
ICC
IP
IHC
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| Novus Biologicals | H00001738-M02 |
1 references | Monoclonal |
WB
EL
IHC
|
|
| Abnova Corporation | H00001738-M02 |
1 references | Monoclonal |
WB
EL
IHC
|
|
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