Tissue expression
Cell line expression
Protein structure
CYP26A1
Cytochrome P450 family 26 subfamily A member 1CP26, CYP26, P450RAI, P450RAI1
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | PA5-24602 | 2 references | Polyclonal |
WB
IHC
FC
OA |
|
antibodies-online | ABIN264502 | 3 references | Monoclonal |
WB
IHC |
|
NovoPro Bioscience Inc. | 128253 | Polyclonal |
WB
EL
IHC
FC |
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Abgent | AP2754d | Polyclonal |
WB
IHC
FC
|
||
NSJ Bioreagents | F40124 | Polyclonal |
WB
IHC
FC
|
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