Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
TREM2
Triggering receptor expressed on myeloid cells 2TREM-2, Trem2a, Trem2b, Trem2c
This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
Top validated antibodies |
|||||
| R&D Systems |  AF1828 |
14 references | Polyclonal |
WB
EL
ICC
FC
|
|
| Novus Biologicals | NBP1-07101 |
3 references | Monoclonal |
WB
EL
ICC
IHC
FC
|
|
| antibodies-online | ABIN449602 |
2 references | Monoclonal |
WB
EL
ICC
FC
|
|
| Bioss | bs-2723R |
3 references | Polyclonal |
WB
ICC
IHC
FC
|
|
| Biorbyt | orb889911 |
Polyclonal |
WB
EL
ICC
IHC
FC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider