KCNK10

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008]

Description

Potassium two pore domain channel subfamily K member 10

Tissue specificity

Tissue enhanced (brain, intestine, stomach)

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Kim et al 2014)

Chromosome

14 (88180103 - 88326907)

Ensembl ID

ENSG00000100433  (ver. 103.38)

Orthologs

Mouse Kcnk10: ENSMUSG00000033854

UniProt

P57789

neXtProt

NX_P57789

Human splice variants
Mouse splice variants

Protein structure