Tissue expression
Cell line expression
Protein structure
NFKBIA
NFKB inhibitor alphaIkappaBalpha, IKBA, MAD-3, NFKBI
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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Proteintech Group | ![]() |
469 references | Polyclonal |
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Novus Biologicals | ![]() |
39 references | Monoclonal |
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GeneTex | ![]() |
4 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
10 references | Monoclonal |
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antibodies-online | ![]() |
33 references | Monoclonal |
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