Tissue expression
Cell line expression
Protein structure
TRIB3
Tribbles pseudokinase 3C20orf97, dJ1103G7.3, TRB3
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]
Top validated antibodies |
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| Proteintech Group | 35 references | Polyclonal |
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| GeneTex | 2 references | Polyclonal |
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| Invitrogen Antibodies | Monoclonal |
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| LSBio | Polyclonal |
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| antibodies-online | Monoclonal |
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