Tissue expression
Cell line expression
Protein structure
JAG1
Jagged canonical Notch ligand 1AGS, AHD, AWS, CD339, HJ1, JAGL1
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Nov 2019]
Top validated antibodies |
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| LSBio | Polyclonal |
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| R&D Systems | 5 references | Polyclonal |
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| Novus Biologicals | 8 references | Polyclonal |
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| OriGene | Polyclonal |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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