RENBP

The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008]

Description

Renin binding protein

Tissue specificity

Tissue enhanced (kidney, lymphoid tissue)

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

X (153935269 - 153944687)

Ensembl ID

ENSG00000102032  (ver. 103.38)

Orthologs

Mouse Renbp: ENSMUSG00000031387

UniProt

P51606

neXtProt

NX_P51606

Human splice variants
Mouse splice variants

Protein structure