Tissue expression
Cell line expression
Protein structure
KLF8
Kruppel like factor 8BKLF3, DXS741, ZNF741
This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Top validated antibodies |
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| NSJ Bioreagents | Polyclonal |
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| antibodies-online | 4 references | Polyclonal |
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| Abnova Corporation | 1 references | Polyclonal |
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| LSBio | Polyclonal |
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| Novus Biologicals | 3 references | Polyclonal |
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