DRP2

Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. The protein encoded by this gene is predicted to resemble certain short C-terminal isoforms of dystrophin and dystrophin-related protein 1 (DRP1 or utrophin). DRP2 is expressed principally in the brain and spinal cord. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

Description

Dystrophin related protein 2

Tissue specificity

Tissue enhanced (brain, lymphoid tissue)

Subcell location

Nuclear speckles, Plasma membrane

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

X (101219769 - 101264502)

Ensembl ID

ENSG00000102385  (ver. 103.38)

Orthologs

Mouse Drp2: ENSMUSG00000000223

UniProt

Q13474

neXtProt

NX_Q13474

Human splice variants
Mouse splice variants

Protein structure