Tissue expression
Cell line expression
Protein structure
COTL1
Coactosin like F-actin binding protein 1CLP
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group | 9 references | Polyclonal |
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| LSBio | Monoclonal |
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| Invitrogen Antibodies | Polyclonal |
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| antibodies-online | 1 references | Monoclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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