Tissue expression
Cell line expression
Protein structure
SFRP1
Secreted frizzled related protein 1FRP, FRP-1, SARP2
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]
Top validated antibodies |
|||||
| Proteintech Group | 4 references | Polyclonal |
|
||
| antibodies-online | 2 references | Polyclonal |
|
||
| R&D Systems | 6 references | Polyclonal |
|
||
| LSBio | Polyclonal |
|
|||
| NSJ Bioreagents | Polyclonal |
|
|||