Tissue expression
Cell line expression
Protein structure
SLC39A14
Solute carrier family 39 member 14KIAA0062, NET34, ZIP14
This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia. [provided by RefSeq, May 2017]
Top validated antibodies |
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Invitrogen Antibodies | PA5-21077 | 6 references | Polyclonal |
WB
ICC
IHC
OA |
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GeneTex | GTX31996 | Polyclonal |
WB
EL
ICC
IHC |
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Novus Biologicals | NBP1-76510 | Polyclonal |
WB
EL
ICC
IHC |
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Boster Biological Technology | A04761 | Polyclonal |
WB
EL
ICC
IHC |
||
antibodies-online | ABIN4354362 | Polyclonal |
WB
EL
ICC
IHC |
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