Tissue expression
Cell line expression
Protein structure
TUSC3
Tumor suppressor candidate 3MagT2, MGC13453, MRT22, MRT7, N33, OST3A, SLC58A2
This gene encodes a protein that has been associated with several biological functions including cellular magnesium uptake, protein glycosylation and embryonic development. This protein localizes to the endoplasmic reticulum and acts as a component of the oligosaccharyl transferase complex which is responsible for N-linked protein glycosylation. This gene is a candidate tumor suppressor gene. Homozygous mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation-7 and in the proliferation and invasiveness of several cancers including metastatic pancreatic cancer, ovarian cancer and glioblastoma multiform. [provided by RefSeq, Oct 2017]
Top validated antibodies |
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LSBio | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
1 references | Polyclonal |
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Proteintech Group | ![]() |
7 references | Polyclonal |
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Cusabio Biotech Co., Ltd | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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