POLR2I

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. [provided by RefSeq, Jul 2008]

Description

RNA polymerase II subunit I

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
RNA polymerase related proteins

Chromosome

19 (36113709 - 36115213)

Ensembl ID

ENSG00000105258  (ver. 103.38)

Orthologs

Mouse Polr2i: ENSMUSG00000019738

UniProt

P36954

neXtProt

NX_P36954

Human splice variants
Mouse splice variants

Protein structure