CLIP3

This gene encodes a member of the cytoplasmic linker protein 170 family. Members of this protein family contain a cytoskeleton-associated protein glycine-rich domain and mediate the interaction of microtubules with cellular organelles. The encoded protein plays a role in T cell apoptosis by facilitating the association of tubulin and the lipid raft ganglioside GD3. The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

Description

CAP-Gly domain containing linker protein 3

Tissue specificity

Tissue enhanced (brain)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

19 (36014660 - 36033343)

Ensembl ID

ENSG00000105270  (ver. 103.38)

Orthologs

Mouse Clip3: ENSMUSG00000013921

UniProt

Q96DZ5

neXtProt

NX_Q96DZ5

Human splice variants
Mouse splice variants

Protein structure