Tissue expression
Cell line expression
Protein structure
ICAM4
Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)CD242, LW
This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| LSBio | Polyclonal |
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| Proteintech Group | 1 references | Monoclonal |
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| Novus Biologicals | 2 references | Polyclonal |
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| antibodies-online | 1 references | Polyclonal |
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| Biorbyt | Polyclonal |
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