Tissue expression
Cell line expression
Protein structure
RASD1
Ras related dexamethasone induced 1AGS1, DEXRAS1
This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Top validated antibodies |
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Atlas Antibodies | HPA047896 | Polyclonal |
WB
ICC
IHC
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Biorbyt | orb449893 | Polyclonal |
WB
EL
ICC
IHC |
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Invitrogen Antibodies | PA5-61617 | Polyclonal |
WB
ICC
IHC
|
||
antibodies-online | ABIN4305061 | Polyclonal |
WB
ICC
IHC
|
||
Novus Biologicals | NBP1-91830 | Polyclonal |
WB
ICC
IHC
|
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