MMD

This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages. [provided by RefSeq, Jul 2008]

Description

Monocyte to macrophage differentiation associated

Tissue specificity

Group enriched (adipose tissue, brain)

Subcell location

Vesicles

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Transporters

Chromosome

17 (55392622 - 55421924)

Ensembl ID

ENSG00000108960  (ver. 103.38)

Orthologs

Mouse Mmd: ENSMUSG00000003948

UniProt

Q15546

neXtProt

NX_Q15546

Human splice variants
Mouse splice variants

Protein structure